{"id":1703,"date":"2014-04-05T09:00:49","date_gmt":"2014-04-05T09:00:49","guid":{"rendered":"http:\/\/indogomagazine.com\/indogo\/?p=1703"},"modified":"2014-04-09T18:28:52","modified_gmt":"2014-04-09T18:28:52","slug":"detect-cancer-early","status":"publish","type":"post","link":"http:\/\/indogomagazine.com\/indogo\/detect-cancer-early\/","title":{"rendered":"Detect Cancer Early"},"content":{"rendered":"<p>Simple Blood Test Could Detect Cancer Early<\/p>\n<p>Detecting many forms of cancer may soon be as easy as a simple blood test, according to a new study.<\/p>\n<div id=\"attachment_1704\" style=\"width: 430px\" class=\"wp-caption alignleft\"><a href=\"http:\/\/indogomagazine.com\/indogo\/wp-content\/uploads\/2014\/04\/Researchers-say-theyve-made-a-breakthrough-in-measuring-cancer-DNA-levels-in-blood..jpg\"><img decoding=\"async\" aria-describedby=\"caption-attachment-1704\" class=\" wp-image-1704\" alt=\"Researchers say they've made a breakthrough in measuring cancer DNA levels in blood.\" src=\"http:\/\/indogomagazine.com\/indogo\/wp-content\/uploads\/2014\/04\/Researchers-say-theyve-made-a-breakthrough-in-measuring-cancer-DNA-levels-in-blood..jpg\" width=\"420\" height=\"auto\" srcset=\"http:\/\/indogomagazine.com\/indogo\/wp-content\/uploads\/2014\/04\/Researchers-say-theyve-made-a-breakthrough-in-measuring-cancer-DNA-levels-in-blood..jpg 1024w, http:\/\/indogomagazine.com\/indogo\/wp-content\/uploads\/2014\/04\/Researchers-say-theyve-made-a-breakthrough-in-measuring-cancer-DNA-levels-in-blood.-300x189.jpg 300w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><p id=\"caption-attachment-1704\" class=\"wp-caption-text\">Researchers say they&#8217;ve made a breakthrough in measuring cancer DNA levels in blood.<\/p><\/div>\n<p>&nbsp;<\/p>\n<p>The blood test, developed by researchers at Stanford University School of Medicine, could also be used to \u201cmonitor the amount of cancer in a patient\u2019s body,\u201d say the researchers, as well as measure their response to various treatments.<\/p>\n<p>The test, called CAPP-Seq, for Cancer Personalized Profiling by deep Sequencing, is a refinement of past approaches to measuring the level of tumor DNA in the patient\u2019s bloodstream, according to the study.<\/p>\n<p>The new method was able to \u201caccurately identify about 50 percent of people in the study with stage-1 lung cancer and all patients whose cancers were more advanced,\u201d according to the researchers.<\/p>\n<p>Researchers said that cancer cells \u201care continuously dividing and dying,\u201d and as they do, they release DNA into the bloodstream. They called these traces of DNA \u201ctiny messages in a bottle.\u201d<\/p>\n<p>Reading these messages, researchers said, can allow better diagnoses and better monitoring of treatment. This blood test would go far toward finding the one mutation in 1,000 or 10,000 that come from cancer cells.<\/p>\n<p>\u201cThe vast majority of circulating DNA is from normal, non-cancerous cells, even in patients with advanced cancer,\u201d said Scott Bratman, another author in a statement. \u201cWe needed a comprehensive strategy for isolating the circulating DNA from blood and detecting the rare, cancer-associated mutations.\u201d<\/p>\n<p>Those not involved in the study were hopeful.<\/p>\n<p>\u201cI think it\u2019s an important advance in the field,\u201d said Dr. Abhijit Patel from Yale Cancer Center and Smilow Cancer Hospital, where he does similar research. \u201cThe goal is to detect very small, early stage tumors.\u201d<\/p>\n<p>Patel said one of the major breakthroughs of the test is the ability to monitor changes in DNA mutations in cancer patients who are already receiving treatment and may develop a resistance to a specific medicine.<\/p>\n<p>He also said the test was very unlikely to produce false positives because cancer \u201cDNA mutations are unlikely to be found in healthy people.\u201d<\/p>\n<p>The study examined patients suffering from non-small-cell lung cancer, but the researchers said the test could be \u201capplicable to many different solid tumors throughout the body.\u201d<\/p>\n<p>In the future, the researchers said the test could be used to \u201cscreen healthy or at-risk populations for signs of trouble.\u201d<\/p>\n<p>\u201cIt may be possible to develop assays that could simultaneously screen for multiple cancers,\u201d said Maximilian Diehn, MD, an author of the study. \u201cThis would include diseases such as breast, prostate, colorectal and lung cancer, for example.\u201d<\/p>\n<p>Patel added that while the breakthrough was promising, it\u2019s likely going to be five or 10 years before a screening test would be available to the general public.<\/p>\n<p>\u201cTo monitor treatment responses or resistance to treatment, it would be closer,\u201d he said.<\/p>\n<p>source: Matthew Hilburn \/ VOA News \/ Nature Medicine<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Simple Blood Test Could Detect Cancer Early Detecting many forms of cancer may soon be as easy as a simple blood test, according to a new study. &nbsp; The blood test, developed by researchers at Stanford University School of Medicine, could also be used to \u201cmonitor the amount of cancer in a patient\u2019s body,\u201d say [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1704,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[49],"tags":[],"class_list":["post-1703","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - 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